Binance Review 2018: Comprehensive Crypto Coin Exchange
Binance is a Chinese cryptocurrency exchange. Binance was created after attracting funds via an ICO (Initial Coin Offering – creating a new digital asset, backed by the project. Changpeng Zhao, former CTO at OKCoin is currently at the helm of Binance. They are known for fast processing speeds coupled with an ability to process enormous numbers of transactions (1.4 million) each second. It’s been quickly gaining ground in market share cementing a place as a top 20 exchange in terms of volume.
Binance transaction has reached a new level and currently score tenth place in the world. Binance offers a generous daily withdrawal limit. They don’t need identity confirmation when the per day remittance is within limit of 2 BTC.
Binance Features
Binance’s trading platform is web-based. Furthermore it offers two distinct trading layouts, a more simple one and a “Pro” version.
Their ICO has created tokens named BNB that are traded on the exchange. They can also be used as a method of paying your trading fees, which will reduce them by 50%. Binance offers their own startup incubator platform as well. The trading functionality of the platform was of more interest so we focused on that for the purposes of this Binance review.
Below is the “standard platform” look:
Below is the advanced display:
BINANCE Advantages
Large Cryptocurrency Pairings Supported
The competitive advantage of Binance’s platform is the ability to trade every major cryptocurrency pairing in existence. Coinbase and Gemini only offer trading of a handful of the larger market capitalization cryptos, whereas Binance allows users access to trade over 100 crypto coins.
Low Fees AND LIMITS
The fee structure is simple as well as being priced. There is a flat 0.10% fee on all trading. The 0.10% fee on trades is one basis point. If you were to buy a cryptocoin at 100 you’d have to sell it higher for 101 to profit.
Ease of Setup
Setting up an account is straight forward, similar to signing up for an account with other service providers. Another advantage is there is no lengthy waiting time, users are able to get setup and running within minutes. This is due to the fact that fiat is not accepted on the exchange.
Binance Provides Significant Trading Volume
Binance is currently the third largest exchange by cryptocurrency trading volume, according to coinmarketcap. At the time of writing, Binance’s volume was an astounding $5,441,711,452 in the last 24 hours! This volume demonstrates their users clear trust in the exchange, as well as the accessibility of the exchange and ease of transacting. This type of volume requires substantial servers and computational power.
Wide Support of Cryptocurrencies
No Verification Requirements
Binance doesn’t require identity confirmation in instances when the per day remittance is within the limit of 2 BTC. The attractiveness of setting up an account with Binance may be greater for a user in a jurisdiction where certain exchanges choose not to allow new users because of restrictions imposed by that location’s governing regulatory bodies.
Ease of Use
You’re able to buy and sell crypto pairings with market or limit orders while specifying the amount or percentage you wish to trade for each transaction.
BINANCE Disadvantages
No Leveraged Margin Trading
Margin trading is not available at Binance. Margin trading is a system which allows you to trade with more money than you actually have in your account. Your balance is then used as a guarantee to maintain your position open.
No Fiat Functionality
This has both advantages and disadvantages. Government fiat deposits are not currently enabled in Binance, instead this exchange focuses only on the digital side of things. Clients can deposit and withdraw the coins supported at the exchange. This means that you’re not able to deposit or withdraw in fiat currency, only cryptocurrency is supported.
Relatively New
Binance was started in only July 2017, according to this Reddit post. This is a major concern, as they don’t have a history. Despite all the good things people are saying on Reddit. it’s worth mentioning as many exchanges have come and gone. Binance appears to have a visible co-founder, unlike BTC-E.
Conclusion
Accessible option for obtaining Different Cryptocoins
Binance is the most rapidly-growing and communally praised cryptocurrency exchange available. It’s China based location may spell issues in the future due to rumors of a “crackdown“. that currently accounts for a large amount of volume. Although Binance targets high frequency traders, it is quite useful for those getting beginning with altcoin trading. Their lack of fiat money deposits may be difficult to swallow for beginners, only supported cryptocurrencies may be deposited. Binance boasts a large number of various cryptocoins for trading.
The main benefit is the ability convert between cryptocurrencies. For instance exchanges such as Coinbase and Gemini are more limited in the number of cryptocurrencies offered. The interface is also conducive to support shorter duration hold time day trading of cryptocurrencies if one were so inclined to deploy that strategy. Binance is an exchange worth looking into and integrating into crypto trading just for their large amount of supported crypto coins.
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How Gilead Plans to Keep Competitors in Check (GILD, ABBV) By Investopedia | April 14, 2015 — 3:38 PM EDT
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Gilead Sciences Inc
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Gilead Sciences (NASDAQ: GILD) has plenty of experience in outmaneuvering competitors. After all, despite competitors' launching new HIV therapies, Gilead Sciences continues to maintain its dominance in the indication. Whether or not Gilead Sciences can leverage its experience in HIV to protect its market share in hepatitis C is being put to the test this year, so let's take a look at Gilead Sciences' pipeline and see how the company plans to thwart its competitors.
Jumping to the front of the pack
Gilead Sciences' decision to acquire Pharmasset for $11.2 billion in 2012 to get its hands on hepatitis C drug Sovaldi has proven to be brilliant.
Previously, hepatitis C patients were treated with a mash-up of injection-based drugs that despite 48-week treatment cycles and nasty side effects offered only coin flip cure rates. Sovaldi was nothing short of a revolutionary change. The treatment, which won FDA approval in December 2013, cuts treatment down to 12 weeks, eliminates the use of side effect-laden peg interferon for many patients, and delivers cure rates north of 90%.
As a result, doctors flocked to Sovaldi following its launch, turning the drug into the fastest drug to eclipse billion dollar blockbuster status and the second best-selling drug on the planet, with $10.3 billion in sales last year.
That's an outstanding accomplishment for a drug as young as Sovaldi, but Sovaldi isn't the only hepatitis C drug that Gilead Sciences launched last year.
In October, the company won approval for Harvoni, a combination of Sovaldi and an NS5A inhibitor named ledipasvir, for use in genotype 1 HCV, the most common variation of the disease. Harvoni delivers mid-90% cure rates and eliminates both peg interferon and ribavirin from HCV treatment regimens.
Similar to Sovaldi, doctors are rushing to embrace Harvoni, leading to $2.1 billion in sales for the drug during just its first quarter on the market.
Thanks to Sovaldi and Harvoni, Gilead Sciences now dominates the market for HCV treatment, but competitors are working on their own hepatitis C medicines that could pose a threat to Gilead Sciences' market share.
Challenging its lead
The first of these competitors to threaten Gilead Sciences' HCV market stranglehold was AbbVie's Viekira Pak.
AbbVie won approval for the multi-drug oral therapy for genotype 1 patients in December and shortly thereafter launched the first salvo in a price battle with Gilead Sciences when it announced that it had inked an exclusivity deal with the pharmacy benefit manager Express Scripts.
Express Scripts has been a vocal advocate for competition in HCV, so it's little surprise to see it move quickly to lock up steep discounts for Viekira Pak in exchange for exclusive status on its drug formula. The deal will save Express Scripts money, but it's also a win for AbbVie since Viekira Pak may have struggled in a head-to-head competition with Harvoni.
Viekira Pak patients typically must take three pills in the morning and one pill in the evening, and patients are likely to continue to need to take ribavirin along with those pills, too.
That's a far more onerous pill burden than Harvoni, which is dosed as one pill daily. Additionally, while Viekira Pak must be taken for 12 weeks in all patients, Harvoni can be dosed over a period of as little as eight weeks in about 40% of genotype 1a patients.
Given that difference in dosing, it's not hard to see why AbbVie determined that its best chance to elbow market share away from Gilead Sciences was through price cuts and an exclusivity deal.
Thwarting that competition
In a bid to reduce the long-term threat of AbbVie's Viekira Pak on its sales, Gilead Sciences is developing its next generation of HCV medications.
Among the furthest along in development is a fixed dose combination pill of Sovaldi and GS-5816. Gilead Sciences is conducting late stage phase 3 trials to evaluate this combination's ability to offer up a peg interferon and ribavirin free option across all genotypes of the disease, not just for genotype 1 patients.
During phase 2 trials, 94.8%-96.1% of genotype 1 through genotype 6 patients receiving this therapy achieved a functional cure at 12 weeks. If those results hold up in phase 3, then this drug could supplant Sovaldi as the pan-genotype drug of choice, while also further limiting the appeal of AbbVie's Viekira Pak.
However, a bigger opportunity for Gilead Sciences to sure up its market share against AbbVie may come from combining Sovaldi, GS-5816, and GS-9857. Gilead Sciences has a slate of phase 2 trials for this two-pill therapy under way, including trials that are evaluating this regimen over a six-, eight-, and 12-week dosing period in genotype 1 patients.
If this combination delivers similar cure rates to AbbVie's Viekira Pak and Harvoni, and it can reduce the treatment duration to as little as six weeks, then it could become the best-in-class option on the market, essentially relegating Viekira Pak to niche status.
Looking ahead
Thanks to its deal with Express Scripts, AbbVie has a very good chance of winning billion-dollar blockbuster status for Viekira Pak this year.
However, Viekira Pak's success may prove to be short lived if new therapies in Gilead Sciences' pipeline pan out. Given that Gilead Sciences has a proven track record of keeping competitors at bay, long-term investors considering AbbVie may want discount any positive impact that Viekira Pak may have on AbbVie's sales this year. Meanwhile, long-term investors considering Gilead Sciences may want to focus less on Viekira Pak's potential negative impact on Harvoni's sales this year and more on Gilead Sciences' next generation HCV drugs.
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Todd Campbell owns shares of Gilead Sciences. Todd owns E.B. Capital Markets, LLC. E.B. Capital's clients may or may not have positions in the companies mentioned.
Read more: How Gilead Plans to Keep Competitors in Check (GILD, ABBV) | Investopedia https://www.investopedia.com/stock-analysis/041415/how-gilead-plans-keep-competitors-check-gild-abbv.aspx#ixzz5LEpnIIbQ
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